CENTER

Center 2 – Systemic Recovery Medical Sciences

The Systemic Recovery Medical Sciences Center investigates the systemic biological processes involved in recovery from post-infectious disease. Research within this center focuses on the complex interactions between inflammation, metabolic regulation, mitochondrial function, and epigenetic signaling that may influence long-term health outcomes following viral infection. Persistent immune activation and unresolved inflammatory responses can disrupt multiple physiological systems simultaneously. This center examines how these systemic changes contribute to fatigue syndromes, metabolic dysfunction, neuroimmune signaling disturbances, and other chronic conditions observed after acute infection. Projects within the center explore mechanisms of mitochondrial dysfunction, chronic inflammation, epigenetic modification, and metabolic imbalance, as well as their potential roles in long-term disease risk. As the integrative hub of the RAPID research framework, the Systemic Recovery Center collaborates closely with cardiovascular, neurological, gastrointestinal, and immunological research programs to understand how systemic biological stressors influence multiple organ systems.